Paradigm Biopharma (PAR) listed on the ASX in August 2015. We focus on repurposing pentosan polysulphate sodium (PPS) for the treatment of conditions that begin with and are sustained by inflammation, where a key feature of the activity of PPS is its anti-inflammatory and tissue regenerative properties. Our lead clinical indications include: treating bone marrow edema (BME), an increasingly recognised pathological change in bone and a significant contributor to pain and symptoms in Osteoarthritis and acute joint injury; and the treatment of joint function, mobility and pain in patients with mucopolysaccharidoses (MPS).
Other indications include treating alphavirus induced arthralgia (in patients with Ross River Virus and Chikungunya); and allergic respiratory conditions, including allergic rhinitis (AR) and chronic obstructive pulmonary disease (COPD).
Adopting an intelligent and agile approach to clinical research and development, our experienced team are passionate in our commitment to the quality of our programmes. We have built and sustained strong and successful collaborations with leading clinical researchers in the field, and continue to develop partnerships with high quality European manufacturers in order to bring new, effective treatments to market.