Announcement PDF ASX RELEASE 10 November 2023 The Manager The Company Announcements Office Australian Securities Exchange via electronic lodgement Paradigm Biopharmaceuticals Limited ACN 169 346 963 (ASX: PAR) RE: NOTICE OF RELEASE OF ESCROWED SECURITIES Pursuant to Listing Rule 3.10A, Paradigm Biopharmaceuticals Limited confirms that 366,667 restricted securities from Company’s Employee Share Plan (ESP) (offer date 19th November 2020, issued at a price of $3.05 per share) will be released from escrow on 19 November 2023. The shares remain under the Company’s Loan Funding agreement as set out in the ESP. The Loan becomes due and payable (unless extended by the Company in its absolute discretion) on the first to occur of the following: a) The Repayment Date (5 years from the date on which the Company advances the Loan to the Participant); b) 90 days after the Participant ceases for any reason to be employed or engaged by the Company; or c) by the legal personal representative of the Participant, six months after the Participant ceases to be an employee or consultant of the Company due to their death. Yours faithfully Abby Macnish Company Secretary This announcement was authorised for release by the Company Secretary. FOR FURTHER INFORMATION PLEASE CONTACT: Simon White Director of Investor Relations Tel: +61 404 216 467 Paradigm Biopharmaceuticals Ltd ABN: 94 169 346 963 Level 15, 500 Collins St, Melbourne, VIC, 3000, AUSTRALIA Email : investorrelations@paradigmbiopharma.com