Announcement PDF Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 1 / 7 Announcement Summary Entity name PARADIGM BIOPHARMACEUTICALS LIMITED.. Announcement Type New announcement Date of this announcement Wednesday June 17, 2026 The +securities to be quoted are: Please refer to the response to Q2.3d for further information about the type of securities to be quoted and the circumstances of the issue. Please refer to announced "Options Prospectus" https://cdn-api.markitdigital.com/apiman-gateway/ASX/asx-research/1.0/f ile/2924-03099444-3A695157&v=undefined Total number of +securities to be quoted ASX +security code Security description Number of +securities to be quoted Issue date New class - code to be confirmed Options expiring 1 December 2026 or 20 BD post IA announcement 117,069,101 15/06/2026 Refer to next page for full details of the announcement Other Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 2 / 7 Part 1 - Entity and announcement details 1.1 Name of entity PARADIGM BIOPHARMACEUTICALS LIMITED.. We (the entity named above) apply for +quotation of the following +securities and agree to the matters set out in Appendix 2A of the ASX Listing Rules. 1.2 Registered number type ACN Registration number 169346963 1.3 ASX issuer code PAR 1.4 The announcement is 1.5 Date of this announcement 17/6/2026 New announcement Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 3 / 7 Part 2 - Type of Issue 2.1 The +securities to be quoted are: Please refer to the response to Q2.3d for further information about the type of securities to be quoted and the circumstances of the issue. 2.2 The +class of +securities to be quoted is: 2.3c Have these +securities been offered under a +disclosure document or +PDS? 2.3c.1 Date of +disclosure document or +PDS? 11/6/2026 2.3d Please provide any further information needed to understand the circumstances in which you are applying to have these +securities quoted on ASX, including why the issue of the +securities has not been previously announced to the market in an Appendix 3B Please refer to announced "Options Prospectus" https://cdn-api.markitdigital.com/apiman-gateway/ASX/asx-research/1.0/f ile/2924-03099444-3A695157&v=undefined Yes New +securities in a class that is not yet quoted on ASX ("new class") Other Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 4 / 7 Part 3C - number and type of +securities to be quoted (new class) where issue has not previously been notified to ASX in an Appendix 3B New +securities ASX +security code New class - code to be confirmed +Security description Options expiring 1 December 2026 or 20 BD post IA announcement +Security type Options ISIN code Issue date 15/6/2026 Will all the +securities issued in this class rank equally in all respects from the issue date? Have you received confirmation from ASX that the terms of the +securities are appropriate and equitable under listing rule 6.1? Distribution Schedule Provide a distribution schedule for the new +securities according to the categories set out in the left hand column - including the number of recipients and the total percentage of the new +securities held by the recipients in each category. Number of +securities held Number of holders Total percentage of +securities held For example, to enter a value of 50% please input as 50.00 1 - 1,000 0 0.00 % 1,001 - 5,000 11 0.04 % 5,001 - 10,000 16 0.12 % 10,001 - 100,000 384 11.34 % 100,001 and over 224 88.50 % Options Details +Security currency AUD - Australian Dollar Exercise price AUD 0.23750000 Expiry date 1/12/2026 Yes Yes Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 5 / 7 Details of the type of +security that will be issued if an option is exercised PAR : ORDINARY FULLY PAID Number of +securities that will be issued if an option is exercised One Ordinary Fully Paid Please provide a URL link for a document lodged with ASX setting out the material terms of the +securities to be quoted or provide the information by separate announcement. https://cdn-api.markitdigital.com/apiman-gateway/ASX/asx-research/1.0/file/2924-03099444-3A695157&v=undefined Issue details Number of +securities to be quoted 117,069,101 Are the +securities being issued for a cash consideration? Please describe the consideration being provided for the +securities N/A Please provide an estimate (in AUD) of the value of the consideration being provided per +security for the +securities to be quoted 0.000000 Any other information the entity wishes to provide about the +securities to be quoted The purpose(s) for which the entity is issuing the securities Other Please provide additional details For the Company's Phase III Clinical Trial activities No Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 6 / 7 Part 4 - Issued capital following quotation Following the quotation of the +securities the subject of this application, the issued capital of the entity will comprise: The figures in parts 4.1 and 4.2 below are automatically generated and may not reflect the entity's current issued capital if other Appendix 2A, Appendix 3G or Appendix 3H forms are currently with ASX for processing. 4.1 Quoted +securities (total number of each +class of +securities quoted on ASX following the +quotation of the +securities subject of this application) ASX +security code and description Total number of +securities on issue PAR : ORDINARY FULLY PAID 576,499,282 New class - code to be confirmed : Options expiring 1 December 2026 or 20 BD post IA announcement 117,069,101 4.2 Unquoted +securities (total number of each +class of +securities issued but not quoted on ASX) ASX +security code and description Total number of +securities on issue PARAAC : PERFORMANCE RIGHTS 12,066,600 PARAR : OPTION EXPIRING 11-FEB-2028 EX $1.00 151,293 PARAAE : OPTION EXPIRING 30-JUN-2027 EX $0.65 3,000,000 PARAAD : CONVERTIBLE NOTES 6,297,185 Appendix 2A - Application for quotation of securities Appendix 2A - Application for quotation of securities 7 / 7 Part 5 - Other Listing Rule requirements 5.1 Are the +securities being issued under an exception in Listing Rule 7.2 and therefore the issue does not need any security holder approval under Listing Rule 7.1? 5.2 Has the entity obtained, or is it obtaining, +security holder approval for the issue under listing rule 7.1? 5.2a Date of meeting or proposed meeting to approve the issue under listing rule 7.1 11/6/2026 Yes No