Appendix 4D and Half Year Report
Released
Released
Announcement PDF
Paradigm Biopharmaceuticals Limited
Appendix 4D
Half-year report
1. Company details
Name of entity:
ABN:
Reporting period:
Previous reporting period:
Paradigm Biopharmaceuticals Limited
94 169 346 963
31 December 2024
31 December 2023
2. Results for announcement to the market
$
Revenue from continuing activities
(Loss) from continuing activities after tax
433,658
$ and %
increase/(decrease) over
previous corresponding
period
221,681
104.58%
(5,924,052)
(44,095,472)
88.16%
Net (loss) for the period attributable to members
(5,921,642)
(44,127,428)
88.17%
Dividends (distributions)
Amount per
Franked amount per
security
security
Final Dividend
N/A
N/A
Interim Dividend
N/A
N/A
attributable to members
Record date for determining entitlements to the
dividends (if any)
N/A
2. Results for announcement to the market continued
Brief explanation of any of the figures reported above necessary to enable the figures to be
understood: Paradigm Biopharmaceuticals Ltd. is a late-stage clinical development company
focusing on advancing its lead Phase 3 asset, iPPS, for the treatment of osteoarthritis. In the
absence of partnering income or material revenue contributions, the company anticipates continued
losses in the near term as it invests in clinical, regulatory, and commercial activities to support the
development of iPPS, which has the potential to become a blockbuster treatment for osteoarthritis.
Paradigm recorded a loss before tax of $5,924,052, a decrease on the prior corresponding period
loss before tax of $50,019,524 (Restated). The decrease in loss before tax compared to the prior
corresponding period of $50.01m, is mainly driven by research and development costs. This
decrease reflects the conclusion of the PARA_OA_002 study, which was instrumental in
determining the optimal 2mg/kg twice-weekly dose to progress into the pivotal Phase 3
PARA_OA_012 study. The majority of expenditure for the PARA_OA_002 study was concluded in
the first half of the 2024 calendar year.
Paradigm Biopharmaceuticals Limited
Appendix 4D
Half-year report
3. Net tangible assets
Basic loss per ordinary security (cents
per share)
Diluted loss per ordinary security
(cents per share)
Net tangible asset backing per ordinary
security (cents per share)
Current Period
Previous corresponding
period (Restated)
(1.67) cents
(16.68) cents
(1.67) cents
(16.68) cents
7.99 cents
8.78 cents
4. Control gained over entities
Not applicable.
5. Loss of control over entities
Not applicable.
6. Audit qualification or review
This report is based on accounts to which one of the following applies:
(Tick one)
The accounts have been reviewed
The accounts are in the process of being
reviewed
If the accounts are subject to audit dispute or qualification, a description of the dispute or
qualification: N/A
7. Attachments
The report of half year ended 31 December 2024 is attached.
8. Signed
Signed _____________________________
Mr. Paul Rennie
Managing Director
27th February 2025
EXPLORING THE POSSIBILITIES
H A L F -Y E A R R E P O R T
31 DECEMBER 2024
Paradigm Biopharmaceuticals Ltd is a late-stage
clinical development company. We are driven by
a purpose to improve patients’ health and quality
of life by discovering, developing, and delivering
pharmaceutical therapies.
Paradigm has a vision to be recognised as a global leader in the development and commercialisation
of innovative pharmaceutical therapies. Paradigm’s values of innovation, transparency, adaptability,
collaboration, respect, and accountability comprise the central pillars of the organisation and influence
all activities and decisions.
Contents
01
Highlights
04
Directors’ Report
07
Auditor’s Independence Declaration
09
10
11
Consolidated Interim Statement
of Cash Flows
12
Consolidated Interim Statement
of Changes in Equity
Consolidated Interim Statement
of Profit or Loss and Other
Comprehensive Income
13
Notes to Financial Statements
18
Directors’ Declaration
onsolidated Interim Statement
C
Financial Position
19
Independent Audit Report
21
Corporate Directory
Paradigm Biopharmaceuticals Limited
ABN 94 169 346 963
HIGHLIGHTS
466
$16m AUD
Subjects will be
randomised 1:1
to iPPS or Placebo
50%
Interim analysis when
50% of participants
have reached Day 112
Capital raised in Q4 to
fund ongoing phase 3
OA program activities
Paradigm’s Road to Phase 3 with the US FDA: Advancing a New Approach
to Osteoarthritis Treatment
Paradigm Biopharmaceuticals is developing injectable pentosan polysulfate sodium (iPPS)
as a potential treatment to reduce OA pain and improve function by exploiting its multiple
effects on inflammation, cartilage integrity, and joint homeostasis. The company’s clinical
program has been shaped by extensive research and ongoing regulatory engagement,
culminating in clearance from the US Food and Drug Administration (FDA) to proceed
with a pivotal phase 3 trial. This milestone represents a significant step forward in
Paradigm’s efforts to develop a new treatment option for people living with OA.
Osteoarthritis (OA) is one of the most
prevalent chronic conditions and affects
>500 million people worldwide. It is a
leading cause of progressive disability,
characterised by pain, reduced joint
function, and structural degeneration.
Treatment options remain largely
focused on symptom relief, with
non-steroidal anti-inflammatory drugs
(NSAIDs), corticosteroid injections,
and joint replacement surgery forming
the backbone of current management
strategies. These interventions offer
varying degrees of relief but do not alter
the underlying disease progression,
leaving a significant unmet need for
new therapies.
Assessing the Lowest Effective Dose (PARA_OA_002)
Paradigm has built a substantial body of
evidence supporting the 2 mg/kg iPPS
twice-weekly for six weeks treatment
regimen, with data from its PARA_
OA_008, PARA_005, and TGA Special
Access Scheme (SAS) programs.
As part of its regulatory interactions
and clinical development strategy, the
company designed an adaptive phase
2b/3 trial, PARA_OA_002, to assess
whether a lower dose of iPPS could
achieve a meaningful reduction in pain
and improvement in function.
The initial stage of PARA_OA_002 was
designed to evaluate the lowest effective
dose, determining whether doses lower
than 2 mg/kg twice weekly for six weeks
could still provide clinically meaningful
benefits. This approach aligned with
regulatory guidance, which encourages
sponsors to explore the minimum
effective dose when developing new
treatments. The trial enrolled 600
participants across seven countries,
making it Paradigm’s largest and most
comprehensive study to date.
Paradigm Biopharmaceuticals Limited
An interim analysis was conducted
when 300 patients reached 56 days
of follow‑up, allowing for an early
assessment of treatment performance
across the different dosing arms.
The findings indicated that the doses
included in PARA_OA_002 Stage
1 did not demonstrate the same
improvements in pain and function
observed with the 2 mg/kg twice‑weekly
for six weeks regimen in previous
phase 2 studies. Clinically meaningful
improvements for the 2 mg/kg dosing
regimen were consistent for the phase
2 clinical trials PARA_OA_008 and
PARA_005, and the TGA SAS scheme.
With these findings, Paradigm
confirmed that its ongoing clinical
development program should focus
on the 2 mg/kg twice-weekly for six
weeks dosing regimen.
Half-Year Report 31 December 2024
01
HIGHLIGHTS CONTINUED
The coming months will be focused on activating sites
in Australia, initiating enrollment activities and trial
execution. As Paradigm moves forward, it remains
committed to engaging with global regulatory agencies,
clinicians, and industry partners to progress iPPS
through the final stages of development.
Regulatory Engagement
and the Path to Phase 3
Clearance
With a clear understanding of the
dosing strategy, Paradigm advanced
its discussions with the FDA to finalise
the phase 3 study design. In January
2024, the company participated in a
Type D meeting with the agency,
outlining its plans for the phase 3
protocol and providing supporting data
from clinical and nonclinical studies.
A formal response package was
submitted to the FDA in April 2024,
addressing key regulatory considerations,
including five nonclinical studies
conducted to Good Laboratory Practice
(GLP) standards. In addition, the package
included clinical data from more than
600 participants in the PARA_OA_002
trial, as well as a justification for the
2 mg/kg twice-weekly regimen based
on findings from previous trials.
Paradigm also submitted a revised
safety monitoring and mitigation plan
and a draft phase 3 protocol for
FDA review.
Following this submission, Paradigm
lodged the updated phase 3 protocol
(PARA_OA_012) on 29 October 2024,
triggering a 30-day FDA review period.
This allowed the agency to assess the
study design, endpoints, and dosing
regimen. On 28 November 2024, the
FDA completed its review with no
further questions, granting Paradigm
clearance to proceed with the phase 3
trial. This outcome was an important
milestone, providing the company
with a clear regulatory path for its
final-stage clinical program.
02
Half-Year Report 31 December 2024
Advancing Towards the
Phase 3 PARA_OA_012 Trial
With FDA clearance secured,
Paradigm has the green light to start
the PARA_OA_012 phase 3 trial,
designed to confirm the safety and
efficacy of iPPS in people with OA.
The study will enrol 466 participants
who will be randomised between iPPS
and placebo groups. The primary
endpoint will assess pain reduction,
with function assessed as a key
secondary endpoint. Multiple secondary
endpoints will be assessed throughout
the phase 3 trial, including MRI/X-raybased structural assessments following
the exciting data produced in the
phase 2 PARA_OA_008 clinical trial.
An interim analysis will be conducted
once data has been collected from 50%
of the participants who have reached
the Day 112 timepoint.
To support the trial’s execution, Paradigm
has selected Advanced Clinical as its
contract research organisation (CRO).
Site start-up activities are expected to
begin in Q1 2025, with up to 10 clinical
sites in Australia preparing to dose the
first participants in Q2 2025. The trial
is then anticipated to expand to the
United States, broadening global
patient recruitment.
The Road Ahead: Delivering
a Potential New Treatment
for OA
Paradigm’s journey to phase 3 clearance
has been guided by ongoing research,
regulatory discussions, and refinement
of its clinical strategy. The PARA_OA_002
study played an important role in
assessing whether a lower dose of iPPS
could be effective, and the results have
shaped the next steps in the company’s
clinical development program.
With the phase 3 PARA_OA_012 trial
now set to begin, Paradigm is positioned
to generate definitive clinical evidence
on iPPS’s role in OA management. If
successful, this program could offer a
new treatment option for OA patients
who currently have limited alternatives
beyond over-the-counter pain relief
and surgery.
The coming months will be focused
on activating sites in Australia, initiating
enrollment activities and trial execution.
As Paradigm moves forward, it remains
committed to engaging with global
regulatory agencies, clinicians, and
industry partners to progress iPPS
through the final stages of development.
For people living with OA, the potential
introduction of iPPS represents an
opportunity for a new approach to pain
relief and improved function, supporting
a better quality of life. With the phase 3
trial activities now underway, Paradigm
continues to take meaningful steps
towards making this treatment a reality.
References:
Data used is available in Paradigm’s public
disclosures to the ASX.
Paradigm Biopharmaceuticals Limited
With the phase 3 PARA_OA_012 trial now set to begin,
Paradigm is positioned to generate definitive clinical
evidence on iPPS’s role in OA management. If successful,
this program could offer a new treatment option for OA
patients who currently have limited alternatives beyond
over-the-counter pain relief and surgery.
Paradigm Biopharmaceuticals Limited
Half-Year Report 31 December 2024
03
DIRECTORS’ REPORT
The Directors present their report,
together with the financial
statements, on the Consolidated
Entity (referred to hereafter as the
‘Consolidated Entity’) consisting
of Paradigm Biopharmaceuticals
Limited (Paradigm or the Company)
and the entities it controlled at the
end of, or during, the half-year
ended 31 December 2024
Directors
The following persons were Directors
of the Company during the whole of
the financial half-year and up to the date
of this report, unless otherwise stated:
Paul Rennie
Amos Meltzer
Matthew Fry
Donna Skerrett
(Resigned on 20 November 2024)
Principal Activities
The principal activities of the
Consolidated Entity are researching
and developing therapeutic products
for human use.
Results
The Consolidated Entity made a loss
for the six-month period ended
31 December 2024 of $5,924,052
(31 December 2023 (restated):
Loss of $50,019,524).
04
Half-Year Report 31 December 2024
Review of Operations
The Board of Paradigm
Biopharmaceuticals are pleased to
present this report for the half-year
ended 31 December 2024. The past
six months have been transformative
for the Company as we advanced
the development of our Phase 3
clinical program for knee osteoarthritis
and strengthened our financial
position to support our long-term
strategic objectives.
In the first half of fiscal year 2025,
Paradigm focused its efforts on essential
regulatory activities and submissions
required for the progression of the phase 3
program. These included comprehensive
regulatory engagements with the U.S.
Food and Drug Administration (FDA) to
secure approval of the pivotal phase 3
PARA_OA_012 protocol.
Paradigm achieved a significant
milestone with the successful completion
of the FDA’s 30-day review period for the
revised phase 3 protocol for the PARA_
OA_012 trial. The protocol, submitted
on 29 October 2024, incorporated key
enhancements based on FDA feedback
and lessons from previous trials. These
include the adoption of the 2mg/kg
twice-weekly dosing regimen, which
has consistently demonstrated positive
outcomes, and a sample size of
approximately 466 subjects randomised
1:1 with placebo to ensure statistical
robustness. Secondary endpoints,
such as structural improvements
Paradigm Biopharmaceuticals Limited
assessed via MRI and X-ray, have been
elevated to strengthen the potential
label claims. The FDA’s clearance of the
protocol enables Paradigm to proceed
with preparations for site activations
and enrollment initiatives, which are
on track to commence in Q1 CY2025.
In parallel, Paradigm submitted the
Australian centralised ethics application
through the Human Research Ethics
Committee (HREC) pathway in Q4
CY2024. This approval process is
expected to conclude in the coming
weeks, allowing the streamlined
activation of up to 10 clinical sites
and the commencement of clinical site
activations. These developments mark
critical steps forward in the execution
of our Phase 3 clinical program.
In December 2024, Paradigm
successfully completed a $16 million
capital raise through a placement to
institutional and sophisticated investors.
This placement involved the issuance
of 40 million shares at $0.40 per share,
representing a 2.9% premium to the
30-day volume-weighted average price.
Following the placement, Paradigm
provided detail on a loyalty option
incentive program, offering one listed
option for every four shares held.
These options, exercisable at $0.65
with a 12-month expiry, could raise
up to an additional $63 million, providing
significant financial runway to support
our clinical and commercial objectives.
Subsequent to the half year close, the
Company received a $6.3 million
Paradigm continues to build on the robust data generated
from the PARA_OA_008 Phase 2 trial. This study
demonstrated durable and significant improvements
in key clinical outcomes, including pain, function,
and stiffness, at 12 months post-treatment with iPPS
compared to placebo.
Research and Development (R&D) Tax
Incentive refund for the 2024 financial year.
This refund further bolstered our cash
position, which totalled $24.78 million
as of 31 December 2024. These funds
have been allocated strategically to
support phase 3 trial preparations,
including regulatory submissions,
site activations, and manufacturing
and inventory requirements.
In terms of financial performance,
Paradigm recorded a loss before tax
of $5,924,052, a decrease on the prior
corresponding period loss before tax
of $50,019,524. As a late-stage clinical
development company, Paradigm is
focused on advancing its lead Phase 3
asset, iPPS, for the treatment of
osteoarthritis. In the absence of
partnering income or material revenue
contributions, the company anticipates
continued losses in the near term as
it invests in clinical, regulatory, and
commercial activities to support the
development of iPPS, which has the
potential to become a blockbuster
treatment for osteoarthritis.
The decrease in loss before tax
compared to the prior corresponding
period of $50.01m, is mainly driven
by research and development costs.
This decrease reflects the conclusion
of the PARA_OA_002 study, which was
instrumental in determining the optimal
2mg/kg twice-weekly dose to progress
into the pivotal Phase 3 PARA_OA_012
study. The majority of expenditure for
the PARA_OA_002 study was concluded
in the first half of the 2024 calendar year.
Operating expenses for the half year
financial year 2025 totalled $2.19 million,
with funds directed toward Phase 3 trial
preparations, regulatory submissions,
and associated operational costs.
Paradigm forecasts a controlled cash
outflow for the remainder of fiscal year
2025, focusing on site activations and
participant recruitment for the phase 3
PARA_OA_002 clinical trial.
Paradigm continues to build on the robust
data generated from the PARA_OA_008
Phase 2 trial. This study demonstrated
durable and significant improvements in
key clinical outcomes, including pain,
function, and stiffness, at 12 months
post-treatment with iPPS compared to
placebo. Quantitative MRI data further
highlighted structural benefits, including
increased cartilage thickness and
reduced bone marrow lesions, reinforcing
iPPS’s dual role in treating osteoarthritis
symptoms and preserving joint health.
These results have been written up as
two manuscripts and submitted to
leading journals for peer review. The first
manuscript details the outcomes of the
PARA_OA_008 Phase 2 trial and the
second manuscript compares the
PARA_OA_008 results to currently
available and pipeline therapies for
osteoarthritis. Peer-reviewed publications
play a critical role in establishing scientific
credibility, enhancing visibility within the
medical community, and providing
validation of the clinical data underpinning
our programs.
Paradigm Biopharmaceuticals Limited
During the half-year, Dr Donna Skerrett,
Paradigm’s Executive Director,
transitioned from her Board role in
November 2024 to focus entirely on her
duties as Chief Medical Officer (CMO).
This decision enables Dr Skerrett to
dedicate her full attention to the
successful execution of the pivotal
Phase 3 clinical trial. Her deep expertise
and leadership remain integral to
Paradigm as we advance iPPS through
this critical phase of development.
During the half-year, the TGA provided
a decision that iPPS would not be
acceptable to continue through the
provisional approval pathway however
acknowledged the clinical benefits
of PPS for moderate to severe knee
osteoarthritis and cited that the
proposed Phase 3 program execution
and strong data produced would provide
the necessary evidence to support full
registration. This determination aligns
with Paradigm’s broader regulatory
strategy and positions the Company to
advance iPPS toward commercialisation.
Other income is higher for the 6 months
to December 2024 mainly due to the
$6,300,439 FY24 R&D tax incentive
claim receivable in January 2025 being
higher than estimated at 30 June 2024.
Interest received has decreased due to
lower cash levels available for investment.
Administration costs decreased
compared to the prior corresponding
period due to the Company’s ongoing
cost containment program.
Half-Year Report 31 December 2024
05
DIRECTORS’ REPORT
continued
Looking ahead, Paradigm is preparing
for several critical milestones in the
second half of FY2025. These include
the initiation of phase 3 recruitment
initiatives in Q1 CY2025 following the
finalisation of the recently announced
selection of Advanced Clinical as
Contract Research Organisation (CRO)
to manage the global trial and the
upcoming centralised ethics approval
in Australia. The Company remains on
track to initiate approximately 10 sites
in Australia for the phase 3 trial with first
participant expected to be dosed in Q2
CY2025. Additionally, the Company is
actively pursuing strategic partnerships
and non/less dilutive funding opportunities
to extend its financial position to bring
iPPS to commercialisation.
The Paradigm Board would like to
take this opportunity to thank our
shareholders for their continued support
as we progress through this pivotal
phase in the development of iPPS. I also
extend my gratitude to the Paradigm
team for their unwavering dedication and
commitment to our mission of delivering
innovative therapies to patients suffering
from osteoarthritis. We remain confident
in the transformative potential of iPPS
and look forward to updating you on
our progress in the months ahead.
Events Subsequent
to Reporting Date
Significant changes
in the State of Affairs
Mr. Paul Rennie
Managing Director
During the period Paradigm conducted
a capital raise of $16m. In October
Paradigm issued 40 million shares
via a placement to institutional investors
at an issue price of $0.40.
27 February 2025
The Company remains on track to initiate
approximately 10 sites in Australia for the
phase 3 trial with first participant expected
to be dosed in Q2 CY2025.
06
Half-Year Report 31 December 2024
Paradigm Biopharmaceuticals Limited
No matters or circumstance has arisen
since 31 December 2024 that has
significantly affected, or may significantly
affect the Consolidated Entity’s operations,
the results of those operations, or the
Consolidated Entity’s state of affairs
in future financial periods.
AUDITOR’S INDEPENDENCE DECLARATION
AUDITOR’S INDEPENDENCE DECLARATION
As lead auditor for the review of the financial report of Paradigm Biopharmaceuticals Limited for the half year
ended 31 December 2024, I declare that to the best of my knowledge and belief, there have been no
contraventions of:
(i)
the auditor independence requirements of the Corporations Act 2001 in relation to the review; and
(ii)
any applicable code of professional conduct in relation to the review.
RSM AUSTRALIA PARTNERS
R J MORILLO MALDONADO
Partner
Dated: 27 February 2025
Melbourne, Victoria
Paradigm Biopharmaceuticals Limited
Half-Year Report 31 December 2024
07
CONSOLIDATED INTERIM FINANCIAL STATEMENTS
Contents
Consolidated Interim Statement of Profit or Loss and Other Comprehensive Income
09
Consolidated Interim Statement of Financial Position
10
Consolidated Interim Statement of Changes in Equity
11
Consolidated Interim Statement of Cash Flows
12
Notes to the Financial Statements
13
Directors’ Declaration
18
Independent Auditor’s Review Report
19
General Information
The financial statements cover Paradigm Biopharmaceuticals Limited as a Consolidated Entity, consisting of Paradigm
Biopharmaceuticals Limited and the entities it controlled at the end of, or during, the half-year ended 31 December 2024.
The financial statements are presented in Australian dollars, which is Paradigm Biopharmaceuticals Limited’s functional
and presentation currency.
Paradigm Biopharmaceuticals Limited is a listed public company limited by shares, incorporated and domiciled in Australia.
Its registered office and principal place of business is:
Level 15, 500 Collins Street
Melbourne VIC 3000
A description of the nature of the Consolidated Entity’s operations and its principal activities are included in the Directors’ report,
which is not part of the financial statements.
The financial statements were authorised for issue, in accordance with a resolution of Directors, on 27th February 2025.
08
Half-Year Report 31 December 2024
Paradigm Biopharmaceuticals Limited
CONSOLIDATED INTERIM STATEMENT OF PROFIT OR LOSS
AND OTHER COMPREHENSIVE INCOME
for the Half-Year Ended 31 December 2024
Revenue
Notes
(18,715)
–
2
416,958
211,977
Cost of sales
Other income
31 December
2023
(Restated)
$
31 December
2024
$
Other gains and (losses)
16,700
–
10,889
(78,356)
Research and development expenses
(3,987,852)
(46,374,458)
General and administration expenses
(2,191,775)
(3,519,024)
Commercial expenses
(166,018)
(253,184)
Finance costs
(4,239)
(6,479)
(5,924,052)
(50,019,524)
–
–
(5,924,052)
(50,019,524)
Foreign currency translation
2,410
(29,546)
Other comprehensive income/(loss) for the half-year, net of tax
2,410
(29,546)
(5,921,642)
(50,049,070)
(1.67) cents
(16.68) cents
Loss before income tax expense/(benefit)
Income tax expense/(benefit)
Loss after income tax expense/(benefit) attributable to the members
of the Consolidated Entity
Other comprehensive income
Items that may be reclassified subsequently to profit or loss
Total comprehensive loss attributable to members of the Consolidated Entity
Loss per share (cents)
Basic and diluted loss per share
7
Refer to note 3 for detailed information on Restatement of comparatives.
The above consolidated interim statement of profit or loss and other comprehensive income is to be read in conjunction with the
accompanying notes.
Paradigm Biopharmaceuticals Limited
Half-Year Report 31 December 2024
09
CONSOLIDATED INTERIM STATEMENT OF FINANCIAL POSITION
as at 31 December 2024
ASSETS
Notes
31 December
2024
$
30 June 2024
(Restated)
$
30 June 2023
(Restated)
$
24,778,341
17,820,827
56,333,085
6,374,203
6,065,980
7,868,438
1,138,494
1,303,662
599,078
–
46,200
46,200
32,291,038
25,236,669
64,846,801
2,947,588
2,947,588
2,947,588
Current assets
Cash and cash equivalents
Trade and other receivables
4
Prepaid expenses
Financial assets held at amortised cost
Total current assets
Noncurrent assets
Intangible assets
Plant and equipment
27,791
31,462
42,601
Right-of-use assets
90,394
158,194
293,791
Total noncurrent assets
3,065,773
3,137,244
3,283,980
Total assets
35,356,811
28,373,913
68,130,781
Trade and other payables
580,837
2,821,157
12,161,182
Employee benefits
414,728
416,812
776,196
Lease liabilities
81,403
121,842
104,971
1,076,968
3,359,811
13,042,349
LIABILITIES
Current liabilities
Total current liabilities
Noncurrent liabilities
Employee benefits
124,665
107,042
112,830
Lease liabilities
100,000
117,488
236,694
Total noncurrent liabilities
224,665
224,530
349,524
Total liabilities
1,301,633
3,584,341
13,391,873
Net assets
34,055,178
24,789,572
54,738,908
EQUITY
Issued capital
5
253,235,141
238,113,171
209,833,883
Share based payments reserve
6
5,161,265
7,549,821
7,786,686
Currency translation reserve
(1,124,347)
(1,126,757)
(428,784)
Accumulated losses
(223,216,881)
(219,746,663)
(162,452,877)
Total equity
34,055,178
24,789,572
54,738,908
Refer to note 3 for detailed information on Restatement of comparatives.
The above consolidated interim statement of financial position should be read in conjunction with the accompanying notes.
10
Half-Year Report 31 December 2024
Paradigm Biopharmaceuticals Limited
CONSOLIDATED INTERIM STATEMENT OF CHANGES IN EQUITY
for the Half-Year Ended 31 December 2024
Balance at 30 June 2023 originally reported
Issued
Capital
$
Currency
Translation
Reserve
$
7,786,686
(163,514,014)
–
1,061,137
–
1,061,137
209,833,883
7,786,686
(162,452,877)
(428,784)
54,738,908
Loss after Income tax expense/(benefit)
for the half-year
–
–
(50,019,524)
–
(50,019,524)
Other comprehensive loss for the half-year,
net of tax
–
–
–
(29,546)
(29,546)
Total comprehensive loss for the half-year
–
–
(50,019,524)
(29,546)
(50,049,070)
Balance at 1 July 2023 – restated
(428,784)
Total
$
–
Correction of Error
209,833,883
Share-based
Payments Accumulated
Losses
Reserve
$
$
53,677,771
Transactions with owners in their capacity
as owners:
Share-based payments expense
–
913,482
–
–
913,482
ESP lapsed in the period
–
(801,552)
718,209
–
(83,343)
Shares issued under placement
21,002,894
–
–
–
21,002,894
Shares issued under retail offer
9,113,960
–
–
–
9,113,960
Payment of share issue costs
(1,837,615)
–
–
–
(1,837,615)
Balance at 31 December 2023
238,113,122
7,898,616
(211,754,192)
(458,330)
33,799,216
Balance at 30 June 2024 originally reported
238,113,171
7,549,821
(220,730,138)
(1,126,757)
23,806,097
–
–
983,475
–
983,475
238,113,171
7,549,821
(219,746,663)
(1,126,757)
24,789,572
Loss after Income tax expense/(benefit)
for the half-year
–
–
(5,924,052)
–
(5,924,052)
Other comprehensive loss for the half-year,
net of tax
–
–
–
2,410
2,410
Total comprehensive loss for the half-year
–
–
(5,924,052)
2,410
(5,921,642)
–
65,280
–
–
65,280
Correction of Error
Balance at 1 July 2024 – restated
Transactions with owners in their capacity
as owners:
Share-based payments expense
ESP lapsed in the period
–
(1,641,178)
1,641,178
–
–
16,000,000
–
–
–
16,000,000
Options exercised in the period
1,027
–
–
–
1,027
Payment of share issue costs
(879,057)
–
–
–
(879,057)
Options lapsed in the period
–
(637,841)
637,841
–
–
Performance ri
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